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Antibody-mediated protection against MERS-CoV in the murine model()

Murine antisera with neutralising activity for the coronavirus causative of Middle East respiratory syndrome (MERS) were induced by immunisation of Balb/c mice with the receptor binding domain (RBD) of the viral Spike protein. The murine antisera induced were fully-neutralising in vitro for two sepa...

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Detalles Bibliográficos
Autores principales: New, R.R.C., Moore, B.D., Butcher, W., Mahood, R., Lever, M.S., Smither, S., O'Brien, L., Weller, S.A., Bayliss, M., Gibson, L.C.D., Macleod, C., Bogus, M., Harvey, R., Almond, N., Williamson, E.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115393/
https://www.ncbi.nlm.nih.gov/pubmed/31178378
http://dx.doi.org/10.1016/j.vaccine.2019.05.074