Recombinant infectious bronchitis coronavirus H120 with the spike protein S1 gene of the nephropathogenic IBYZ strain remains attenuated but induces protective immunity

Infectious bronchitis (IB) is a highly infectious viral disease responsible for major economic losses in the poultry industry. A reverse genetic vaccine is a safe, rapid, and effective method of achieving IB prevention and control. In this study, we constructed the recombinant strain, rH120-S1/YZ, u...

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Detalles Bibliográficos
Autores principales: Jiang, Yi, Cheng, Xu, Zhao, Xiumei, Yu, Yan, Gao, Mingyan, Zhou, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115396/
https://www.ncbi.nlm.nih.gov/pubmed/32057575
http://dx.doi.org/10.1016/j.vaccine.2020.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115396/
https://www.ncbi.nlm.nih.gov/pubmed/32057575
http://dx.doi.org/10.1016/j.vaccine.2020.01.001

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