A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells

The purpose of this study was to evaluate the enhancement value of chloroquine analogs when used in combination with Akt inhibitors on the MDA-MB468, MDA-MB231 and MCF7 human breast cancer cell lines. The result showed that the combination of certain chloroquine analogs and Akt inhibitors are highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Changkun, Raja Solomon, V., Cano, Pablo, Lee, Hoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115421/
https://www.ncbi.nlm.nih.gov/pubmed/19945197
http://dx.doi.org/10.1016/j.ejmech.2009.11.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115421/
https://www.ncbi.nlm.nih.gov/pubmed/19945197
http://dx.doi.org/10.1016/j.ejmech.2009.11.017

Ejemplares similares