rOv-ASP-1, a recombinant secreted protein of the helminth Onchocercavolvulus, is a potent adjuvant for inducing antibodies to ovalbumin, HIV-1 polypeptide and SARS-CoV peptide antigens

We studied the adjuvanticity of recombinant Onchocerca volvulus activation associated protein-1 (rOv-ASP-1) for ovalbumin (OVA) in mice. After a single immunization and one boost, rOv-ASP-1 exceeded the efficacy of alum or MPL + TDM adjuvants in terms of end-point total IgG or IgG1 and IgG2a anti-OV...

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Detalles Bibliográficos
Autores principales: MacDonald, Angus J., Cao, Long, He, Yuxian, Zhao, Qian, Jiang, Shibo, Lustigman, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115491/
https://www.ncbi.nlm.nih.gov/pubmed/15837368
http://dx.doi.org/10.1016/j.vaccine.2005.01.098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115491/
https://www.ncbi.nlm.nih.gov/pubmed/15837368
http://dx.doi.org/10.1016/j.vaccine.2005.01.098

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