Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety

Hexadecyloxypropyl esters of acyclic nucleoside phosphonates containing guanine (G) or hypoxanthine (Hx) and a (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] [(S)-HPMP] or 2-(2-phosphonoethoxy)ethyl (PEE) acyclic moiety have been prepared. The activity of the prodrugs was evaluated in vitro against diff...

Descripción completa

Detalles Bibliográficos
Autores principales: Tichý, Tomáš, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan, Dračínský, Martin, Krečmerová, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115494/
https://www.ncbi.nlm.nih.gov/pubmed/22858222
http://dx.doi.org/10.1016/j.ejmech.2012.07.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115494/
https://www.ncbi.nlm.nih.gov/pubmed/22858222
http://dx.doi.org/10.1016/j.ejmech.2012.07.027

Ejemplares similares