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Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells
The 2′,5′-oligoadenylate synthetase 1 (OAS1) is one of the major interferon-inducible proteins and a critical component of the host defense system against viral infection. A single nucleotide polymorphism (SNP), rs10774671, presumably responsible for alternate splicing of this gene, has frequently b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115495/ https://www.ncbi.nlm.nih.gov/pubmed/23220500 http://dx.doi.org/10.1016/j.humimm.2012.11.011 |