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Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells

The 2′,5′-oligoadenylate synthetase 1 (OAS1) is one of the major interferon-inducible proteins and a critical component of the host defense system against viral infection. A single nucleotide polymorphism (SNP), rs10774671, presumably responsible for alternate splicing of this gene, has frequently b...

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Detalles Bibliográficos
Autores principales:	Noguchi, Satoshi, Hamano, Emi, Matsushita, Ikumi, Hijikata, Minako, Ito, Hideyuki, Nagase, Takahide, Keicho, Naoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115495/ https://www.ncbi.nlm.nih.gov/pubmed/23220500 http://dx.doi.org/10.1016/j.humimm.2012.11.011

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