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Augmentation of immune responses to SARS coronavirus by a combination of DNA and whole killed virus vaccines

We studied the immunogenicity of a DNA SARS-vaccine, a whole killed virus, or a whole killed and DNA vaccine combination. The DNA vaccine contained a plasmid encoding the SARS coronavirus (SARS-CoV) S protein under the control of the human CMV promoter and intron A. The whole killed virus vaccine wa...

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Detalles Bibliográficos
Autores principales: Zakhartchouk, Alexander N., Liu, Qiang, Petric, Martin, Babiuk, Lorne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115501/
https://www.ncbi.nlm.nih.gov/pubmed/16005746
http://dx.doi.org/10.1016/j.vaccine.2005.04.011