2,6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV)

In this study, as a bioisosteric alternative scaffold of the antiviral aryl diketoacids (ADKs), we used 5-hydroxychromone on which two arylmethyloxy substituents were installed. The 5-hydroxychromones (5b–5g) thus prepared showed anti-HCV activity and, depending on the aromatic substituents on the 2...

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Detalles Bibliográficos
Autores principales: Kim, Mi Kyoung, Yu, Mi-Sun, Park, Hye Ri, Kim, Kyung Bo, Lee, Chaewoon, Cho, Suh Young, Kang, Jihoon, Yoon, Hyunjun, Kim, Dong-Eun, Choo, Hyunah, Jeong, Yong-Joo, Chong, Youhoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2011
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115508/
https://www.ncbi.nlm.nih.gov/pubmed/21925774
http://dx.doi.org/10.1016/j.ejmech.2011.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115508/
https://www.ncbi.nlm.nih.gov/pubmed/21925774
http://dx.doi.org/10.1016/j.ejmech.2011.09.005

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