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Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents

Ebola virus (EBOV) infections cause lethal hemorrhagic fever in humans, resulting in up to 90% mortality. EBOV outbreaks are sporadic and unpredictable in nature; therefore, a vaccine that is able to provide durable immunity is needed to protect those who are at risk of exposure to the virus. This s...

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Detalles Bibliográficos
Autores principales: Wong, Gary, Audet, Jonathan, Fernando, Lisa, Fausther-Bovendo, Hugues, Alimonti, Judie B., Kobinger, Gary P., Qiu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115511/
https://www.ncbi.nlm.nih.gov/pubmed/25173474
http://dx.doi.org/10.1016/j.vaccine.2014.08.028