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A vesicular stomatitis virus-based mucosal vaccine promotes dendritic cell maturation and elicits preferable immune response against coxsackievirus B3 induced viral myocarditis

Recombinant vesicular stomatitis virus (VSV) is widely used as a vaccine platform. However, the capacity of VSV-based vaccines to induce mucosal immunity has not been fully investigated. In the present study, a recombinant VSV expressing coxsackievirus B3 (CVB3) major immunogen VP1 has been generate...

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Detalles Bibliográficos
Autores principales: Wu, Fei, Fan, Xingjuan, Yue, Yan, Xiong, Sidong, Dong, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115516/
https://www.ncbi.nlm.nih.gov/pubmed/24874923
http://dx.doi.org/10.1016/j.vaccine.2014.05.052