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A novel Chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines

The use of adenovirus (Ad) as vaccine vectors is hindered by pre-existing immunity to human Ads in most of the human population. In order to overcome this limitation, uncommon alternative Ad serotypes need to be utilized. In this study, an E1–E3 deleted recombinant Ad based on the chimpanzee serotyp...

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Detalles Bibliográficos
Autores principales: Peruzzi, Daniela, Dharmapuri, Sridhar, Cirillo, Agostino, Bruni, Bruno Ercole, Nicosia, Alfredo, Cortese, Riccardo, Colloca, Stefano, Ciliberto, Gennaro, La Monica, Nicola, Aurisicchio, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115565/
https://www.ncbi.nlm.nih.gov/pubmed/19162112
http://dx.doi.org/10.1016/j.vaccine.2008.12.051