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N-Propargylated isatin-Mannich mono- and bis-adducts: Synthesis and preliminary analysis of in vitro activity against Tritrichomonas foetus

Cu(I)Cl promoted synthesis of N-propargylated-isatin Mannich mono- and bis-adducts with an extension towards the synthesis of N-propargylated-isatin-7-chloroquinoline conjugates was described. The synthesized scaffolds were evaluated for their in vitro activity against the veterinary protozoal patho...

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Detalles Bibliográficos
Autores principales: Nisha, Kumar, Kewal, Bhargava, Gaurav, Land, Kirkwood M., Chang, Kai-Hsiang, Arora, Reena, Sen, Somdutta, Kumar, Vipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115568/
https://www.ncbi.nlm.nih.gov/pubmed/24561663
http://dx.doi.org/10.1016/j.ejmech.2014.01.015