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Immunisation with virion-loaded plasmacytoid or myeloid dendritic cells induces primary Th-1 immune responses

Dendritic cells (DCs) induce different types of immune responses depending on their lineage and activation signals. When exposed to inactivated pseudorabiesvirus (iPRV), plasmacytoid but not myeloid DCs released IFN-α and IL-12. Remarkably, both iPRV-pulsed DC types were able to induce primary IFN-γ...

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Detalles Bibliográficos
Autores principales: Wit, Marel C. de, Horzinek, Marian C., Haagmans, Bart L., Schijns, Virgil E.J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115573/
https://www.ncbi.nlm.nih.gov/pubmed/15661382
http://dx.doi.org/10.1016/j.vaccine.2004.09.014