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Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents

Six series of semisynthetic lipophilic glycopeptide antibiotic derivatives were evaluated for in vitro activity against influenza A and B viruses. The new teicoplanin pseudoaglycon-derived lipoglycopeptides were prepared by coupling one or two side chains to the N-terminus of the glycopeptide core,...

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Detalles Bibliográficos
Autores principales: Szűcs, Zsolt, Kelemen, Viktor, Le Thai, Son, Csávás, Magdolna, Rőth, Erzsébet, Batta, Gyula, Stevaert, Annelies, Vanderlinden, Evelien, Naesens, Lieve, Herczegh, Pál, Borbás, Anikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115582/
https://www.ncbi.nlm.nih.gov/pubmed/30170320
http://dx.doi.org/10.1016/j.ejmech.2018.08.058