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High-cell-density cultivations to increase MVA virus production

Increasing the yield and the productivity in cell culture-based vaccine manufacturing using high-cell-density (HCD) cultivations faces a number of challenges. For example, medium consumption should be low to obtain a very high concentration of viable host cells in an economical way but must be balan...

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Detalles Bibliográficos
Autores principales: Vázquez-Ramírez, Daniel, Genzel, Yvonne, Jordan, Ingo, Sandig, Volker, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115588/
https://www.ncbi.nlm.nih.gov/pubmed/29433897
http://dx.doi.org/10.1016/j.vaccine.2017.10.112