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High-cell-density cultivations to increase MVA virus production
Increasing the yield and the productivity in cell culture-based vaccine manufacturing using high-cell-density (HCD) cultivations faces a number of challenges. For example, medium consumption should be low to obtain a very high concentration of viable host cells in an economical way but must be balan...
Autores principales: | Vázquez-Ramírez, Daniel, Genzel, Yvonne, Jordan, Ingo, Sandig, Volker, Reichl, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115588/ https://www.ncbi.nlm.nih.gov/pubmed/29433897 http://dx.doi.org/10.1016/j.vaccine.2017.10.112 |
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