Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents

Forty-six conjugated derivatives of caudatin with substituted cinnamic acids were synthesized, and their anti-hepatitis B virus (HBV) activity was evaluated in HepG 2.2.15 cells. Most of the derivatives exhibited potent anti-HBV activity, especially inhibiting the HBV DNA replication with the IC(50)...

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Detalles Bibliográficos
Autores principales: Wang, Li-Jun, Geng, Chang-An, Ma, Yun-Bao, Luo, Jie, Huang, Xiao-Yan, Chen, Hao, Zhou, Ning-Jia, Zhang, Xue-Mei, Chen, Ji-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115590/
https://www.ncbi.nlm.nih.gov/pubmed/22687441
http://dx.doi.org/10.1016/j.ejmech.2012.05.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115590/
https://www.ncbi.nlm.nih.gov/pubmed/22687441
http://dx.doi.org/10.1016/j.ejmech.2012.05.012

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