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Avian coronavirus infectious bronchitis attenuated live vaccines undergo selection of subpopulations and mutations following vaccination

In this study, we were interested in determining if high titered egg adapted modified live infectious bronchitis virus (IBV) vaccines contain spike gene related quasispecies that undergo selection in chickens, following vaccination. We sequenced the spike glycoprotein of 12 IBV vaccines (5 different...

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Detalles Bibliográficos
Autores principales: McKinley, Enid T., Hilt, Deborah A., Jackwood, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115600/
https://www.ncbi.nlm.nih.gov/pubmed/18262691
http://dx.doi.org/10.1016/j.vaccine.2008.01.006