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A killed Leishmania vaccine with sand fly saliva extract and saponin adjuvant displays immunogenicity in dogs

A vaccine against canine visceral leishmaniasis (CVL), comprising Leishmania braziliensis promastigote protein, sand fly gland extract (SGE) and saponin adjuvant, was evaluated in dog model, in order to analyse the immunogenicity of the candidate vaccine. The vaccine candidate elicited strong antige...

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Detalles Bibliográficos
Autores principales: Giunchetti, Rodolfo Cordeiro, Corrêa-Oliveira, Rodrigo, Martins-Filho, Olindo Assis, Teixeira-Carvalho, Andréa, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Coura-Vital, Wendel, Abreu, Raquel Tropia de, Malaquias, Luiz Cosme Cotta, Gontijo, Nelder Figueiredo, Brodskyn, Cláudia, Oliveira, Camila Indiani de, Costa, Dirceu Joaquim, de Lana, Marta, Reis, Alexandre Barbosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115610/
https://www.ncbi.nlm.nih.gov/pubmed/18180079
http://dx.doi.org/10.1016/j.vaccine.2007.11.057