Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcγRII-dependent entry into B cells in vitro

Vaccine-induced antibodies can prevent or, in the case of feline infectious peritonitis virus, aggravate infections by coronaviruses. We investigated whether a recombinant native full-length S-protein trimer (triSpike) of severe acute respiratory syndrome coronavirus (SARS-CoV) was able to elicit a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kam, Yiu Wing, Kien, François, Roberts, Anjeanette, Cheung, Yan Chung, Lamirande, Elaine W., Vogel, Leatrice, Chu, Shui Ling, Tse, Jane, Guarner, Jeannette, Zaki, Sherif R., Subbarao, Kanta, Peiris, Malik, Nal, Béatrice, Altmeyer, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115629/
https://www.ncbi.nlm.nih.gov/pubmed/17049691
http://dx.doi.org/10.1016/j.vaccine.2006.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115629/
https://www.ncbi.nlm.nih.gov/pubmed/17049691
http://dx.doi.org/10.1016/j.vaccine.2006.08.011

Ejemplares similares