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SARS-CoV spike protein-expressing recombinant vaccinia virus efficiently induces neutralizing antibodies in rabbits pre-immunized with vaccinia virus

A vaccine for severe acute respiratory syndrome (SARS) is being intensively pursued against its re-emergence. We generated a SARS coronavirus (SARS-CoV) spike protein-expressing recombinant vaccinia virus (RVV-S) using highly attenuated strain LC16m8. Intradermal administration of RVV-S into rabbits...

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Detalles Bibliográficos
Autores principales: Kitabatake, Masahiro, Inoue, Shingo, Yasui, Fumihiko, Yokochi, Shoji, Arai, Masaaki, Morita, Kouichi, Shida, Hisatoshi, Kidokoro, Minoru, Murai, Fukashi, Le, Mai Quynh, Mizuno, Kyosuke, Matsushima, Kouji, Kohara, Michinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115632/
https://www.ncbi.nlm.nih.gov/pubmed/17011679
http://dx.doi.org/10.1016/j.vaccine.2006.08.039