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Immunological characterizations of the nucleocapsid protein based SARS vaccine candidates

The recombinant nucleocapsid (rN) protein of the coronavirus (CoV) responsible for severe acute respiratory syndrome (SARS) was cloned and expressed in Escherichia coli, extracted from cell lysates containing 6 M urea, then purified by Ni(2+)-affinity chromatography. In animal immunogenicity studies...

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Detalles Bibliográficos
Autores principales: Liu, Shih-Jen, Leng, Chih-Hsiang, Lien, Shu-pei, Chi, Hsiang-Yun, Huang, Chiung-Yi, Lin, Chang-Ling, Lian, Wei-Cheng, Chen, Chi-Ju, Hsieh, Shie-Liang, Chong, Pele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115648/
https://www.ncbi.nlm.nih.gov/pubmed/16494977
http://dx.doi.org/10.1016/j.vaccine.2006.01.058