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Immunological characterizations of the nucleocapsid protein based SARS vaccine candidates
The recombinant nucleocapsid (rN) protein of the coronavirus (CoV) responsible for severe acute respiratory syndrome (SARS) was cloned and expressed in Escherichia coli, extracted from cell lysates containing 6 M urea, then purified by Ni(2+)-affinity chromatography. In animal immunogenicity studies...
Autores principales: | Liu, Shih-Jen, Leng, Chih-Hsiang, Lien, Shu-pei, Chi, Hsiang-Yun, Huang, Chiung-Yi, Lin, Chang-Ling, Lian, Wei-Cheng, Chen, Chi-Ju, Hsieh, Shie-Liang, Chong, Pele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115648/ https://www.ncbi.nlm.nih.gov/pubmed/16494977 http://dx.doi.org/10.1016/j.vaccine.2006.01.058 |
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