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H7 virus-like particles assembled by hemagglutinin containing H3N2 transmembrane domain and M1 induce broad homologous and heterologous protection in mice

Influenza A H7N9 virus has caused five outbreak waves of human infections in China since 2013 and posed a dual challenge to public health and poultry industry. There is an urgent need to develop an effective vaccine to reduce its pandemic potential. In the present study, we evaluated the biochemical...

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Detalles Bibliográficos
Autores principales: Qin, Jianru, Zhang, Yun, Shen, Xiaoting, Gong, Lang, Peng, Ouyang, Liu, Yuan, Xue, Chunyi, Cao, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115656/
https://www.ncbi.nlm.nih.gov/pubmed/30037418
http://dx.doi.org/10.1016/j.vaccine.2018.07.004