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A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralising and protective antibody responses

A double-inactivated, candidate whole virus vaccine against severe acute respiratory syndrome associated coronavirus (SARS-CoV) was developed and manufactured at large scale using fermenter cultures of serum protein free Vero cells. A two step inactivation procedure involving sequential formaldehyde...

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Detalles Bibliográficos
Autores principales: Spruth, Martin, Kistner, Otfried, Savidis-Dacho, Helga, Hitter, Elisabeth, Crowe, Brian, Gerencer, Marijan, Brühl, Peter, Grillberger, Leopold, Reiter, Manfred, Tauer, Christa, Mundt, Wolfgang, Barrett, P. Noel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115667/
https://www.ncbi.nlm.nih.gov/pubmed/16214268
http://dx.doi.org/10.1016/j.vaccine.2005.08.055