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Synthesis of 4-aminoquinoline–pyrimidine hybrids as potent antimalarials and their mode of action studies
One of the most viable options to tackle the growing resistance to the antimalarial drugs such as artemisinin is to resort to synthetic drugs. The multi-target strategy involving the use of hybrid drugs has shown promise. In line with this, new hybrids of quinoline with pyrimidine have been synthesi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Masson SAS.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115683/ https://www.ncbi.nlm.nih.gov/pubmed/23811093 http://dx.doi.org/10.1016/j.ejmech.2013.05.046 |