Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase

The outbreak of SARS, a life-threatening disease, has spread over many countries around the world. So far there is no effective drug for the treatment of SARS. Stimulated by the binding mechanism of SARS-CoV M(pro) with the octapeptide AVLQSGFR reported recently as well as the “Chou's distorted...

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Detalles Bibliográficos
Autores principales: Gan, Yi-Ru, Huang, He, Huang, Yong-Dong, Rao, Chun-Ming, Zhao, Yang, Liu, Jin-Sheng, Wu, Lei, Wei, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115688/
https://www.ncbi.nlm.nih.gov/pubmed/16242214
http://dx.doi.org/10.1016/j.peptides.2005.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115688/
https://www.ncbi.nlm.nih.gov/pubmed/16242214
http://dx.doi.org/10.1016/j.peptides.2005.09.006

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