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Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase
The outbreak of SARS, a life-threatening disease, has spread over many countries around the world. So far there is no effective drug for the treatment of SARS. Stimulated by the binding mechanism of SARS-CoV M(pro) with the octapeptide AVLQSGFR reported recently as well as the “Chou's distorted...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115688/ https://www.ncbi.nlm.nih.gov/pubmed/16242214 http://dx.doi.org/10.1016/j.peptides.2005.09.006 |