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3D genome organization during lymphocyte development and activation

Chromosomes have a complex three-dimensional (3D) architecture comprising A/B compartments, topologically associating domains and promoter–enhancer interactions. At all these levels, the 3D genome has functional consequences for gene transcription and therefore for cellular identity. The development...

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Detalles Bibliográficos
Autores principales: van Schoonhoven, Anne, Huylebroeck, Danny, Hendriks, Rudi W, Stadhouders, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115705/
https://www.ncbi.nlm.nih.gov/pubmed/31819944
http://dx.doi.org/10.1093/bfgp/elz030