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HECTD1 regulates the expression of SNAIL: Implications for epithelial-mesenchymal transition

As a transcription factor, SNAIL plays a crucial role in embryonic development and cancer progression by mediating epithelial-mesenchymal transition (EMT); however, post-translational modifications, such as ubiquitination, which control the degradation of SNAIL have been observed to affect its funct...

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Detalles Bibliográficos
Autores principales: Wang, Xinggang, De Geyter, Christian, Jia, Zanhui, Peng, Ya, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115742/
https://www.ncbi.nlm.nih.gov/pubmed/32319576
http://dx.doi.org/10.3892/ijo.2020.5002