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A SARS-CoV protein, ORF-6, induces caspase-3 mediated, ER stress and JNK-dependent apoptosis

Severe acute respiratory syndrome (SARS) coronavirus (CoV) spread from China to more than 30 countries, causing severe outbreaks of atypical pneumonia and over 800 deaths worldwide. CoV primarily infects the upper respiratory and gastrointestinal tract; however, SARS-CoV has a unique pathogenesis be...

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Detalles Bibliográficos
Autores principales: Ye, Zhongde, Wong, Chung Kai, Li, Peng, Xie, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115782/
https://www.ncbi.nlm.nih.gov/pubmed/18708124
http://dx.doi.org/10.1016/j.bbagen.2008.07.009