The structure and oxidation of the eye lens chaperone αA-crystallin

The small heat shock protein (sHsp) αA-crystallin is a molecular chaperone important for the optical properties of the vertebrate eye lens. It forms heterogeneous oligomeric ensembles. We determined the structures of human αA-crystallin oligomers combining cryo-electron microscopy, cross-linking/mas...

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Detalles Bibliográficos
Autores principales: Kaiser, Christoph J. O., Peters, Carsten, Schmid, Philipp W. N., Stavropoulou, Maria, Zou, Juan, Dahiya, Vinay, Mymrikov, Evgeny V., Rockel, Beate, Asami, Sam, Haslbeck, Martin, Rappsilber, Juri, Reif, Bernd, Zacharias, Martin, Buchner, Johannes, Weinkauf, Sevil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115824/
https://www.ncbi.nlm.nih.gov/pubmed/31792453
http://dx.doi.org/10.1038/s41594-019-0332-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115824/
https://www.ncbi.nlm.nih.gov/pubmed/31792453
http://dx.doi.org/10.1038/s41594-019-0332-9

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