Synthesis of Vicinal Quaternary All-Carbon Centers via Acid-catalyzed Cycloisomerization of Neopentylic Epoxides

[Image: see text] We report our studies on the development of a catalytic cycloisomerization of 2,2-disubstituted neopentylic epoxides to produce highly substituted tetralins and chromanes. Termination of the sequence occurs via Friedel–Crafts-type alkylation of the remote (hetero)arene linker. The...

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Detalles Bibliográficos
Autores principales: Schmid, Matthias, Sokol, Kevin R., Wein, Lukas A., Torres Venegas, Sofia, Meisenbichler, Christina, Wurst, Klaus, Podewitz, Maren, Magauer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115968/
https://www.ncbi.nlm.nih.gov/pubmed/32806198
http://dx.doi.org/10.1021/acs.orglett.0c02296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115968/
https://www.ncbi.nlm.nih.gov/pubmed/32806198
http://dx.doi.org/10.1021/acs.orglett.0c02296

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