Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

Although mouse infection models have been extensively used to study the host response to Mycobacterium tuberculosis, their validity in revealing determinants of human TB resistance and disease progression has been heavily debated. Here, we show that the modular transcriptional signature in the blood...

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Detalles Bibliográficos
Autores principales: Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116040/
https://www.ncbi.nlm.nih.gov/pubmed/32205882
http://dx.doi.org/10.1038/s41590-020-0610-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116040/
https://www.ncbi.nlm.nih.gov/pubmed/32205882
http://dx.doi.org/10.1038/s41590-020-0610-z

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