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Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis
Although mouse infection models have been extensively used to study the host response to Mycobacterium tuberculosis, their validity in revealing determinants of human TB resistance and disease progression has been heavily debated. Here, we show that the modular transcriptional signature in the blood...
Autores principales: | Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116040/ https://www.ncbi.nlm.nih.gov/pubmed/32205882 http://dx.doi.org/10.1038/s41590-020-0610-z |
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