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Progress, Challenges, and Surprises in Annotating the Human Genome

Our understanding of the human genome has continuously expanded since its draft publication in 2001. Over the years, novel assays have allowed us to progressively overlay layers of knowledge above the raw sequence of A’s, T’s, G’s, and C’s. The reference human genome sequence is now a complex knowle...

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Detalles Bibliográficos
Autores principales: Zerbino, Daniel R., Frankish, Adam, Flicek, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116059/
https://www.ncbi.nlm.nih.gov/pubmed/32421357
http://dx.doi.org/10.1146/annurev-genom-121119-083418