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Targeted inhibition of mRNA translation initiation factors as a novel therapeutic strategy for mature B-cell neoplasms

Cancer development is frequently associated with dysregulation of mRNA translation to enhance both increased global protein synthesis and translation of specific mRNAs encoding oncoproteins. Thus, targeted inhibition of mRNA translation is viewed as a promising new approach for cancer therapy. In th...

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Detalles Bibliográficos
Autores principales: Taylor, Joe, Yeomans, Alison M, Packham, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116065/
https://www.ncbi.nlm.nih.gov/pubmed/32924027
http://dx.doi.org/10.37349/etat.2020.00002