Hypoxia-induced TGF-β–RBFOX2–ESRP1 axis regulates human MENA alternative splicing and promotes EMT in breast cancer

Hypoxic microenvironment heralds epithelial–mesenchymal transition (EMT), invasion and metastasis in solid tumors. Deregulation of alternative splicing (AS) of several cancer-associated genes has been instrumental in hypoxia-induced EMT. Our study in breast cancer unveils a previously unreported mec...

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Detalles Bibliográficos
Autores principales: Ahuja, Neha, Ashok, Cheemala, Natua, Subhashis, Pant, Deepak, Cherian, Anna, Pandkar, Madhura R, Yadav, Pooja, Narayanan S.S., Vishnu, Mishra, Jharna, Samaiya, Atul, Shukla, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Cancer-specific RNAs and RNA Processing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116222/
https://www.ncbi.nlm.nih.gov/pubmed/33089214
http://dx.doi.org/10.1093/narcan/zcaa021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116222/
https://www.ncbi.nlm.nih.gov/pubmed/33089214
http://dx.doi.org/10.1093/narcan/zcaa021

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