BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages

In response to environmental stimuli, macrophages change their nutrient consumption and undergo an early metabolic adaptation that progressively shapes their polarization state. During the transient, early phase of pro-inflammatory macrophage activation, an increase in tricarboxylic acid (TCA) cycle...

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Detalles Bibliográficos
Autores principales: Ko, Jeong-Hun, Olona, Antoni, Papathanassiu, Adonia E., Buang, Norzawani, Park, Kwon-Sik, Costa, Ana S. H., Mauro, Claudio, Frezza, Christian, Behmoaras, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116427/
https://www.ncbi.nlm.nih.gov/pubmed/33148611
http://dx.doi.org/10.1242/jcs.247957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116427/
https://www.ncbi.nlm.nih.gov/pubmed/33148611
http://dx.doi.org/10.1242/jcs.247957

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