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Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema

Wnt/β-catenin signaling regulates progenitor cell fate decisions during lung development and in various adult tissues. Ectopic activation of Wnt/β-catenin signaling promotes tissue repair in emphysema, a devastating lung disease with progressive loss of parenchymal lung tissue. The identity of Wnt/β...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Ng-Blichfeldt, John-Poul, Ota, Chiharu, Ciminieri, Chiara, Ren, Wenhua, Hiemstra, Pieter S., Stolk, Jan, Gosens, Reinoud, KΠnigshoff, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116441/
https://www.ncbi.nlm.nih.gov/pubmed/32526076
http://dx.doi.org/10.1002/stem.3241