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Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma

OBJECTIVE: Hepatocellular carcinoma (HCC) is the fastest-growing cause of cancer-related mortality with chronic viral hepatitis and non-alcoholic steatohepatitis (NASH) as major aetiologies. Treatment options for HCC are unsatisfactory and chemopreventive approaches are absent. Chronic hepatitis C (...

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Detalles Bibliográficos
Autores principales: Jühling, Frank, Hamdane, Nourdine, Crouchet, Emilie, Li, Shen, El Saghire, Houssein, Mukherji, Atish, Fujiwara, Naoto, Oudot, Marine A, Thumann, Christine, Saviano, Antonio, Roca Suarez, Armando Andres, Goto, Kaku, Masia, Ricard, Sojoodi, Mozhdeh, Arora, Gunisha, Aikata, Hiroshi, Ono, Atsushi, Tabrizian, Parissa, Schwartz, Myron, Polyak, Stephen J, Davidson, Irwin, Schmidl, Christian, Bock, Christoph, Schuster, Catherine, Chayama, Kazuaki, Pessaux, Patrick, Tanabe, Kenneth K, Hoshida, Yujin, Zeisel, Mirjam B, Duong, François HT, Fuchs, Bryan C, Baumert, Thomas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116473/
https://www.ncbi.nlm.nih.gov/pubmed/32217639
http://dx.doi.org/10.1136/gutjnl-2019-318918