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Decoding the PTM-switchboard of Notch

The developmentally indispensable Notch pathway exhibits a high grade of pleiotropism in its biological output. Emerging evidence supports the notion of post-translational modifications (PTMs) as a modus operandi controlling dynamic fine-tuning of Notch activity. Although, the intricacy of Notch pos...

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Detalles Bibliográficos
Autores principales: Antfolk, Daniel, Antila, Christian, Kemppainen, Kati, Landor, Sebastian K.-J., Sahlgren, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116576/
https://www.ncbi.nlm.nih.gov/pubmed/31301363
http://dx.doi.org/10.1016/j.bbamcr.2019.07.002