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Epigenetic gene silencing by heterochromatin primes fungal resistance

Genes embedded in H3 lysine 9 methylation (H3K9me)–dependent heterochromatin are transcriptionally silenced(1–3). In fission yeast, Schizosaccharomyces pombe, H3K9me-mediated heterochromatin can be transmitted through cell division provided the counteracting demethylase Epe1 is absent(4,5). Under ce...

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Detalles Bibliográficos
Autores principales: Torres-Garcia, Sito, Yaseen, Imtiyaz, Shukla, Manu, Audergon, Pauline N. C. B., White, Sharon A., Pidoux, Alison L., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116710/
https://www.ncbi.nlm.nih.gov/pubmed/32908306
http://dx.doi.org/10.1038/s41586-020-2706-x