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STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

Metastatic melanoma is hallmarked by its ability of phenotype switching to more slowly proliferating, but highly invasive cells. Here, we tested the impact of signal transducer and activator of transcription 3 (STAT3) on melanoma progression in association with melanocyte inducing transcription fact...

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Detalles Bibliográficos
Autores principales: Swoboda, Alexander, Soukup, Robert, Eckel, Oliver, Kinslechner, Katharina, Wingelhofer, Bettina, Schörghofer, David, Sternberg, Christina, Pham, Ha T. T., Vallianou, Maria, Horvath, Jaqueline, Stoiber, Dagmar, Kenner, Lukas, Larue, Lionel, Poli, Valeria, Beermann, Friedrich, Yokota, Takashi, Kubicek, Stefan, Krausgruber, Thomas, Rendeiro, André F., Bock, Christoph, Zenz, Rainer, Kovacic, Boris, Aberger, Fritz, Hengstschläger, Markus, Petzelbauer, Peter, Mikula, Mario, Moriggl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116782/
https://www.ncbi.nlm.nih.gov/pubmed/33323974
http://dx.doi.org/10.1038/s41388-020-01584-6