Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants

Patient Derived Explants (PDEs) represent the direct culture of fragments of freshly-resected tumour tissue under conditions that retain the original architecture of the tumour. PDEs have advantages over other preclinical cancer models as platforms for predicting patient-relevant drug responses in t...

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Detalles Bibliográficos
Autores principales: Miles, Gareth J, Powley, Ian, Mohammed, Seid, Howells, Lynne, Pringle, J. Howard, Hammonds, Tim, MacFarlane, Marion, Pritchard, Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116793/
https://www.ncbi.nlm.nih.gov/pubmed/33318618
http://dx.doi.org/10.1038/s41374-020-00511-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116793/
https://www.ncbi.nlm.nih.gov/pubmed/33318618
http://dx.doi.org/10.1038/s41374-020-00511-3

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