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Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum

Protein synthesis is an energetically costly, complex and risky process. Aberrant protein biogenesis can result in cellular toxicity and disease, with membrane-embedded proteins being particularly challenging for the cell. In order to protect the cell from consequences of defects in membrane protein...

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Detalles Bibliográficos
Autores principales: Phillips, Ben P., Miller, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116877/
https://www.ncbi.nlm.nih.gov/pubmed/33247003
http://dx.doi.org/10.1242/jcs.251983