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Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum
Protein synthesis is an energetically costly, complex and risky process. Aberrant protein biogenesis can result in cellular toxicity and disease, with membrane-embedded proteins being particularly challenging for the cell. In order to protect the cell from consequences of defects in membrane protein...
Autores principales: | Phillips, Ben P., Miller, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116877/ https://www.ncbi.nlm.nih.gov/pubmed/33247003 http://dx.doi.org/10.1242/jcs.251983 |
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