The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPR(mt)). However, how UPR(mt) regulators are orchestrated to transcriptionally activate stress responses remains largely unknown. Here we identified CBP-1, the wo...

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Detalles Bibliográficos
Autores principales: Li, Terytty Yang, Sleiman, Maroun Bou, Li, Hao, Gao, Arwen W., Mottis, Adrienne, Bachmann, Alexis Maximilien, El Alam, Gaby, Li, Xiaoxu, Goeminne, Ludger J. E., Schoonjans, Kristina, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116894/
https://www.ncbi.nlm.nih.gov/pubmed/33718883
http://dx.doi.org/10.1038/s43587-020-00025-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116894/
https://www.ncbi.nlm.nih.gov/pubmed/33718883
http://dx.doi.org/10.1038/s43587-020-00025-z

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