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The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress
Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPR(mt)). However, how UPR(mt) regulators are orchestrated to transcriptionally activate stress responses remains largely unknown. Here we identified CBP-1, the wo...
Autores principales: | Li, Terytty Yang, Sleiman, Maroun Bou, Li, Hao, Gao, Arwen W., Mottis, Adrienne, Bachmann, Alexis Maximilien, El Alam, Gaby, Li, Xiaoxu, Goeminne, Ludger J. E., Schoonjans, Kristina, Auwerx, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116894/ https://www.ncbi.nlm.nih.gov/pubmed/33718883 http://dx.doi.org/10.1038/s43587-020-00025-z |
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